Positive effect of fetal cell microchimerism on tumor presentation and outcome in papillary thyroid cancer
نویسندگان
چکیده
منابع مشابه
Fetal cell microchimerism in papillary thyroid cancer: a possible role in tumor damage and tissue repair.
Fetal cells enter the maternal circulation during pregnancy and can persist in the maternal blood or tissues for decades, creating a physiologic microchimerism. Because papillary thyroid cancer (PTC) is more frequent in women, the role of persisting fetal male cells in this tumor has been investigated. Tumor tissue specimens were obtained from 63 women with PTC who had a male pregnancy before t...
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متن کاملFetal microchimerism and cancer.
The persistence of fetal stem cells with multilineage potential in women who have been pregnant, a phenomenon known as fetal microchimerism, is emerging as a potential contributing factor in certain diseases, including cancer. For example, fetal microchimerism has been implicated in autoimmune disease, wound healing, and cancer. Studies of this phenomenon may provide a novel perspective on canc...
متن کاملFetal cell microchimerism and cancer: a nexus of reproduction, immunology, and tumor biology.
Fetal cell microchimerism (FCM) is the persistence of fetal cells in the maternal circulation and organs following pregnancy. Proposed hypotheses about the function of fetal cells in the pathogenesis of maternal cancer include promotion of tumorigenesis, protection by providing immunosurveillance, and participation in tissue repair. To date, studies of FCM and cancer have been primarily descrip...
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ژورنال
عنوان ژورنال: Chimerism
سال: 2014
ISSN: 1938-1956,1938-1964
DOI: 10.1080/19381956.2015.1107254